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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
26.67
Human Site:
S483
Identified Species:
48.89
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
S483
F
H
H
R
V
S
V
S
D
D
V
G
M
D
A
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S497
F
H
H
R
V
S
V
S
D
D
V
G
M
D
A
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
S483
F
H
H
R
V
S
V
S
D
D
V
G
M
D
T
Dog
Lupus familis
XP_537704
2182
240593
S492
F
H
H
R
V
S
V
S
D
D
V
G
M
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
S483
F
H
H
R
V
S
V
S
D
E
I
G
M
D
T
Rat
Rattus norvegicus
NP_001100505
2040
223488
T388
R
T
N
D
V
A
K
T
P
Q
M
H
G
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
S479
F
H
H
R
A
S
I
S
D
D
V
A
M
E
T
Chicken
Gallus gallus
XP_415884
2225
244861
S527
F
H
H
R
V
S
I
S
D
D
V
A
M
E
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
N429
C
S
C
S
R
L
K
N
Q
K
Q
R
A
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
V554
R
Q
K
L
W
N
F
V
D
P
M
Q
K
A
P
Honey Bee
Apis mellifera
XP_393643
1982
216109
Q330
C
E
H
P
L
L
S
Q
Q
E
L
Q
A
A
T
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
K615
G
D
S
V
K
Q
T
K
Q
L
S
A
V
K
R
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
93.3
93.3
N.A.
80
6.6
N.A.
66.6
80
N.A.
0
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
33.3
N.A.
80
93.3
N.A.
13.3
N.A.
20
26.6
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
0
0
24
16
16
24
% A
% Cys:
16
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
8
0
0
0
0
62
47
0
0
0
39
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
16
0
0
0
16
8
% E
% Phe:
54
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
39
8
0
0
% G
% His:
0
54
62
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
16
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
8
0
8
0
16
8
0
8
0
0
8
8
0
% K
% Leu:
0
0
0
8
8
16
0
0
0
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
54
0
0
% M
% Asn:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
8
% P
% Gln:
0
8
0
0
0
8
0
8
24
8
8
16
0
0
0
% Q
% Arg:
16
0
0
54
8
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
0
8
8
8
0
54
8
54
0
0
8
0
0
0
8
% S
% Thr:
0
8
0
0
0
0
8
8
0
0
0
0
0
8
39
% T
% Val:
0
0
0
8
54
0
39
8
0
0
47
0
8
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _